Ivan Řehoř

building B BS62

Work Experience

  • 2015 – 2018
    Marie Curie Fellow at Utrecht University, in the Group of Physical and Colloidal Chemistry (Willem Kegel), lithographic synthesis of responsive hydrogel systems.
  • 2010–2014
    researcher at Institute of Organic Chemistry and Biochemistry, Czech Academy of Sciences in the group of Petr Cigler, development of nanoparticles for diagnosis and therapy, including nanodiamonds and noble metal core-shell particles.
  • 05/2007–10/2007
    Marie Curie fellow at Delft University of Technology in the group of Joop Peters, development of nanoparticle-based MRI contrast agents



  • PhD,  2006–2011
    Charles University Prague, Department of Inorganic Chemistry, Development of theranostic nanoprobes based on inorganic nanoparticles
  • Masters, 2000-2006
    Charles University Prague, Department of Inorganic Chemistry, Synthesis of symmetric tetraazaphospinic acids

International Experience

Short stays:

  • 05/2011
    1 month at ENS Cachan, France (prof. Francois Treussart), study of optical properties of nanodiamond and their chemical modification with biocompatible polymers
  • 05/2012
    1 month at Case Western Reserve University, USA (prof. Nicole Steinmetz), vectoring of noble metal core-shell nanoparticles, in-vitro and in-vivo study
  • 12/2013
    2 weeks at Case Western Reserve University, USA (prof. Nicole Steinmetz), noble metal core-shell nanoparticles as contrast agents for photoacustic imaging
  • 05/2014
    2 weeks Georgia Institute of Technology, USA (prof. M.G. Finn), construction of supported lipid bilayers on inorganic nanoparticle surface


Grant supports:

2016-2018, Marie Currie Action, Individual Fellowsip “ColloidLego”, project no. 705805

2015-2016, Utrecht University – Sustainibility Talent Grant

2008-2009, Grant Agency of Charles University “Surface Modified Oxidic Materials as MRI Contrast Agents” project number: 70208


PhD. thesis awarded by Second position in “Prix de Chimie” competition of PhD projects organized by embassy of France and Rhodia company (under the auspices of Professor Jean-Marie Lehn)

Master degree thesis awarded by prize of “Hlávkova nadace” foundation


Research Interests

  • Soft Robotics
  • Tissue engineering
  • Drug delivery
  • Responsive Hydrogels
  • Self-Assembly
  • Microfluidics
  • Lithography



Junior Research Grant of the Czech Science Foundation “Templated Synthesis of Hydrogel Microparticles for Biomedical Applications”


  1. I. Rehor, S. van Vreeswijk, T. Vermonden, W. E. Hennink, W. K. Kegel, H. B. Eral, “Biodegradable microparticles for simultaneous detection of counter-feit and deteriorated edible products” Small, 2017, DOI: 10.1002/smll.201701804.
  2. V. Petrakova, I. Rehor, J. Stursa, M. Ledvina, M. Nesladek, P. Cigler, „Charge-Sensitive Fluorescent Nanosensors Created from Nanodiamond“ Nanoscale 2015, 7, 12307-12311.
  3. I. Rehor, K. L. Lee, K. Chen, M. Hajek, J. Havlik, J. Lokajova, M. Masat, J. Slegerova, S. Shukla, H. Heidari, S. Bals, N. F. Steinmetz, P. Cigler, „Plasmonic Nanodiamonds: Targeted Core–Shell Type Nanoparticles for Cancer Cell Thermoablation“ Adv. Healthcare Mater. 2015, 4, 460–468.
  4. J. Slegerova, M. Hajek, I. Rehor, F. Sedlak, J. Stursa, M. Hruby, P. Cigler, „Designing the nanobiointerface of fluorescent nanodiamonds: highly selective targeting of glioma cancer cells“ Nanoscale 2015, 7, 415–420.
  5. Z. Chu, S. Zhang, B. Zhang, C. Zhang, C.-Y. Fang, I. Rehor, P. Cigler, H.-C. Chang, G. Lin, R. Liu, Q. Li, „Unambiguous observation of shape effects on cellular fate of nanoparticles“ Scientific Reports 2014, 4, 4495.
  6. I. Rehor, P. Cigler, “Precise Estimation of HPHT Nanodiamond Size Distribution Based on Transmission Electron Microscopy Image Analysis” Diam. Relat. Mat. Diam. Relat. Mat. 2014, 46, 21-24.
  7. I. Rehor, H. Mackova, S. K. Filippov, J. Kucka, V. Proks, J. Slegerova, S. Turner, G. Van Tendeloo, M. Ledvina, M. Hruby, P. Cigler, “Fluorescent Nanodiamonds with Bioorthogonally Reactive Protein-Resistant Polymeric Coatings“ ChemPlusChem 2014, 79 (1), 21–24.
  8. I. Rehor, J. Slegerova, J. Kucka, V. Proks, V. Petrakova, M.-P. Adam, F. Treussart, S. Turner, S. Bals, P. Sacha, M. Ledvina, A. M. Wen, N. F. Steinmetz, P. Cigler, “Fluorescent Nanodiamonds Embedded in Biocompatible Translucent Shells”, Small 2014, 10 (6), 1106–1115.
  9. I. Řehoř, L. Macháčková, A. Bučánková, S. Matějková, K. Černá, J. Straka, “Measuring the sugar consumption of larvae in bumblebee micro-colonies: a promising new method for tracking food economics in bees”, Apidologie 2014, 45, 116–128.
  10. Z. Berkova, D. Jirak, K. Zacharovova, I. Lukes, Z. Kotkova, J. Kotek, M. Kacenka, O. Kaman, I. Rehor, M. Hajek, F. Saudek “Gadolinium- and Manganite-Based Contrast Agents with Fluorescent Probes for Both Magnetic Resonance and Fluorescence Imaging of Pancreatic Islets: A Comparative Study”, ChemMedChem 2013, 8, 614–621.
  11. J. Havlik, V. Petrakova, I.  Rehor, V. Petrak, M. Gulka, J. Stursa, J. Kucka, J. Ralis, T. Rendler, S.–Y. Lee, R. Reuter, J. Wrachtrup, M. Ledvina, M. Nesladek, P. Cigler, “Boosting nanodiamond fluorescence: towards development of brighter probes”, Nanoscale 2012, 5, 3208-3211.
  12. I. Řehoř, V. Vilímová, P. Jendelová, V. Kubíček, D. Jirák, V. Herynek, M. Kapcalová, J. Kotek, J. Černý, P. Hermann, I. Lukeš „Phosphonate–Titanium Dioxide Assemblies: Platform for Multimodal Diagnostic–Therapeutic Nanoprobes“ J. Med. Chem2011, 54, 5185–5194.
  13. I. Řehoř, V. Kubíček, J. Kotek, P. Hermann, J. Száková, I. Lukeš “Modification of nanocrystalline TiO2 with phosphonate- and bisphosphonate-bearing macrocyclic complexes: sorption and stability studies“ Eur. J. Inorg. Chem. 2011, 1981.
  14. I. Řehoř, V. Kubíček, J. Kotek, P. Hermann, I. Lukeš, J. Száková, L. Vander Elst, R. N. Muller, J. A. Peters1H NMR Relaxivity of Aqueous Suspensions of Titanium Dioxide Nanoparticles Coated with a Gadolinium(iii) Chelate of a  DOTA-monoamide with a Phenylhosphonate Pendant Arm“ J. Mater Chem. 2009, 19, 1494–1500.
  15. V. Kubíček, I. Řehoř, J. Havlíčková, J. Kotek, I. Císařová, P. Hermann, I. Lukeš “Synthesis and Coordination Behavior of Symmetrical Tetraamine Phosphinic Acids”, Eur. J. Inorg. Chem. 2007, 3881–3891.

Book chapters:

J. Slegerova, I. Rehor, J. Havlik, H. Raabova, E. Muchova, P. Cigler, “Nanodiamonds as Intracellular Probes for Imaging in Biology and Medicine” in Intracellular Delivery II (Eds.: A. Prokop, Y. Iwasaki, A. Harada), Springer Netherlands, 2014, pp. 363–401.

I. Rehor, J. Slegerova, J. Havlik, H. Raabova, J. Hyvl, E. Muchova, P. Cigler “Behavior in Biological Systems and Emerging Bioapplications” in Carbon Nanomaterials for Biomedical Applications, Springer International Publishing Switzerland 2016, pp. 319-361