Our recent publication titled “Computational prodrug design methodology for liposome formulability enhancement of small-molecule APIs” has been featured on the cover page of Molecular Pharmaceutics. The paper, authored by Martin Balouch in cooperation with Kateřina Storchmannová and Karel Berka from Palacký University Olomouc and kindly supported by The PARC, reports on a new computational strategy for the design of prodrugs in order to modify their permeation rate across lipid bilayers. This is important both for poorly permeating substances to improve their bioavailability, and for very rapidly permeating substances to enable their formulation into liposomes.